Primobolan, also known as Primo for short, is a brand name for the anabolic steroid methenolone acetate. This steroid is designed for oral administration, but an injectable version is also available. The injectable format of the drug is known as methenolone enanthate, and is marketed under the trade name Primobolan Depot.

A Brief History of Primobolan

The methenolone hormone’s properties and details were first published and released in 1960. But it was not until 1962 that both the oral acetate and injectable enanthate forms became commercially available. It was manufactured by Squibb, a global biopharmaceutical company, which released the injectable enanthate form first followed by the oral variant of the drug. The drugs were both marketed under the brand name Nibal – Nibal (for the oral format) and Nibal Depot (for the injectable variant).

Shortly thereafter, the rights for manufacture of methenolone hormone were acquired by Schering, a German pharmaceutical giant, which withdrew the drug from the American market in the mid-1960s. The company eventually went on to market the drug as an internationally exclusive drug, under the new brand name Primobolan. While methenolone never returned to the American market, doctors in the nation were still allowed to import the hormone on special order.

The early 1990s saw Schering cease production of the methenolone hormone following the increasingly growing concerns over the adverse health effects of anabolic steroids and the anti-steroid sentiment of that time period, which also forced other manufacturers to pull most anabolic steroids from all markets. Because of this, pharmaceutical grade primo is today only found in extremely small amounts in a small select number of markets across the globe.

Primobolan Traits

This anabolic steroid product is derived from Dyhydrostestosterone (DHT) and is essentially a modified form of DHT. It features the same chemical structure as DHT, with a double-bond at carbon 1 and carbon 2 atoms added to boost the compound’s anabolic properties. It also has an added 1-methyl group, which enables the steroid to resist hepatic breakdown during the first pass through the liver.

The drug is made up of the same active steroidal hormone in methenolone, but has an acetate ester that further boosts its resistance against hepatic metabolism. This makes the Primobolan tablet a unique oral steroid, since it does not utilize a C 17-aa alteration to protect itself against oxidation and hepatic breakdown; but rather has a 1-methyl group (1 alkylation) and an acetate ester (17-beta esterification) for this purpose. It is actually one of the few oral anabolic steroids that lack the standard C 17-aa structure, which means it does not cause liver toxicity.

However, oral Primobolan tends to be milder compared to the injectable Primobolan Depot and many other anabolic-androgenic steroids. This can be attributed to the fact the 1 alkylation and 17-beta esterification of the compound do not protect the steroid very well during the first pass through the liver, so much of the initial dose never even makes it to the circulatory system. Primobolan, therefore, requires higher doses in order to achieve the same performance enhancing capacity as other anabolic steroids – which may prove impractical given the high cost of this drug. Ideally, Primobolan is stacked with other anabolic steroids and it can be a great addition to a well-planned cycle.

Primobolan Benefits for Bodybuilders In The UK

Although both androgenic and anabolic ratings of Primobolan are very low, the steroid still possesses a significant performance enhancing capacity. Like other anabolic steroids, this steroid product has been shown to be effective in enhancing protein synthesis and boosting red blood cell count. Primobolan is also known to cause a dramatic improvement in nitrogen retention. These two effects ensure that the body is in the optimal condition for building lean muscle tissue.

Another important benefit of Primobolan is the one related to its strong androgen receptor binding affinity. Its ability to bind with high affinity to the androgen receptor has been proven to directly stimulate lypolysis. While all anabolic steroids provide enhanced metabolic rate necessary for fat burning, Primobolan stands out from the rest by promoting direct fat loss. This, along with its ability to support increased lean tissue growth, makes Primobolan an ideal steroid for the cutting phase.

The other important benefit of buying Primobolan online for bodybuilders in the UK, is its ability to improve the immune system. Supplementing with methenolone hormone produces beneficial effects on the immune system. And this is one of the reasons why it has been used to successfully treat AIDS. The steroid’s immune boosting capabilities, coupled with its ability to promote lean muscle growth, also allow it to provide an effective treatment for muscle wasting diseases and a variety of other conditions, such as sarcopenia, osteoporosis, malnutrition, underweight and premature children.

So men or male bodybuilders should not expect to achieve great or dramatic gains in muscle mass with this steroid, and it is virtually useless in off-season bulking cycle. Instead, Primobolan is best utilized when there’s a specific need for a mild anabolic agent, particularly during the cutting phases of training. When used as a cutting steroid, Primobolan facilitates burning of excess body fat whilst also protecting lean muscle tissue. This produces great conditioning effects, allowing the muscles to appear harder and more defined.

Nonetheless, women can actually use this steroid in an off-season bulking cycle and achieve significant mass gains. This can be attributed to the fact that women are more sensitive to steroids than men; and even a mild anabolic agent can be helpful in realizing bulking effects. In fact, this hormone is one of the best steroids for women in Ireland since it’s very mild and safe. Its mild nature and excellent safety rating have seen it being used successfully to treat children and premature infants.

The final benefit of Primobolan for bodybuilders is its ability to boost strength, which results in improved athletic performance. Like other anabolic steroids, Primo helps the body recover more quickly after a workout. This improves muscle endurance and lets bodybuilders to train harder and more often for optimal results.

Primobolan Side Effects for Bodybuilders

Although Primobolan is one of the mildest and friendliest steroid product available in the market today, it can still cause unwanted side effects. These Primobolan side effects, fortunately, are often very mild – like the drug itself – and easy to control or avoid with responsible use. They include androgenic and cardiovascular side effects as well as suppression of natural testosterone production. This steroid is not associated with any estrogenic side effects or hepatotoxicity.

The estrogenic side effects of Primobolan include: body hair growth, accelerated hair loss in individuals predisposed to male pattern baldness and acne. These side effects can be easily managed through the use of 5-alpha reductase inhibitors.

It is also worth noting that while the steroid is very mild, it is still strong enough to cause virilization symptoms in women if used irresponsibly. Such symptoms include: deepening of the vocal chords, clitoral enlargement and body hair growth. But the likelihood, and severity, of these symptoms will depend on individual sensitivity.

As is the case with other anabolic steroids, Primobolan use produces a negative effect on cholesterol levels. It suppresses HDL (good) cholesterol and increases LDL (bad) cholesterol, but it has little or no effect on blood pressure – which means normal blood pressure can be maintained while using this product. To ensure healthy cholesterol levels, users should implement a cholesterol friendly diet, rich in omega fatty acids and low in simple sugars and saturated fats.

Lastly, genuine Primobolan use will suppress the production of natural testosterone, just like other anabolic steroids. In order to avoid the health problems and issues associated with low testosterone, bodybuilders should implement an appropriate Post Cycle Therapy (PCT) plan once use is discontinued.