The drug clomiphene citrate, commonly referred to as Clomid, is used in the medical world to treat women’s infertility. Due to the fact that Clomid 50mg shows the pronounced ability to block/minimize the effects of estrogen on the body and also elevate production of both the follicle stimulating hormone (FSH) and (primarily) luteinizing hormone (LH) which in turn cause the natural release of testosterone production (responsible for athletic qualities in men), this drug has thus being incorporated in bodybuilding circles in the UK.
In bodybuilding, Clomid is prescribed for its multiple health benefits and less side-effects compared to anabolic/androgenic steroids. Clomid, being an anti-estrogen helps in restoring the normal testosterone production of the body. Anabolic steroids, especially androgens are known to cause inhibition of the body’s own testosterone production. At the end of a steroid cycle, natural production of testosterone in the body of a bodybuilder is zero and since the levels of steroids taken in the blood starts diminishing, this result in loss of muscle tissue gained during the cycle.
On top of the fact that most anabolic/androgenic steroids convert to estrogen through a process called aromatase, this leads to estrogenic related side-effects the most prominent being, Gynecomastia, which is enlargement of male breasts. Although Clomid does not actually reduce the amount of estrogen in the body, it helps in blocking it from attaching itself to receptors and this helps in reducing steroids negative side-effects. For athletes/bodybuilders who want to completely do away with the production of estrogen, stronger medications such as aromatase inhibitors Arimidex or Letrozole are often needed. They work well in the sense that they both reduce estrogen levels and block it from attaching to receptors.
Clomid is also very helpful during the post-cycle testosterone (PCT) crash. At the conclusion of a steroid cycle, endogenous testosterone levels in the body are depressed. This normally causes a dramatic loss in size and strength once the anabolic steroids are removed. This is because in the absence of testosterone, catabolic hormone cortisol dominates in muscle protein synthesis, bringing a catabolic metabolism that eats away all the muscles gained in the steroid cycle.
Thus it is fundamental to introduce exogenous testosterone, since the body at this time is unable to produce the normal testosterone levels on its own.
Thankfully, Clomid acts as a stimulator of the pituitary gland which in turn leads to the production of FSH and LH hormones. Adequate release of these hormones signals the testicles to resume the normal production of testosterone. Given the fundamental importance of testosterone in retaining steroid gains, Clomid is a safe drug to use during PCT.